Member of the Breuss Laboratory
*shared first-author
$shared corresponding author
Breuss Laboratory
Pitsch JW, Wirth SA, Costantino NT, Mejia J, Doss RM, Warren AVA, Yang X, Breuss MW. CREPE (CREate Primers and Evaluate): a computational tool for large-scale primer design and specificity analysis. bioRxiv. 2025.
Doss RM, Lopez-Ignacio S, Dischler A, Hiatt L, Dashnow H, Breuss MW$, Dias CM$. Mosaicism in Short Tandem Repeat Disorders: A Clinical Perspective. Genes (Basel). 2025;16(2). Epub 20250213. doi: 10.3390/genes16020216. PubMed PMID: 40004546; PMCID: PMC11855715.
Doss RM, Breuss MW. A somatic view of the genomic impact of mitochondrial endosymbiosis. PLoS Biol. 2024;22(8):e3002756. Epub 20240823. doi: 10.1371/journal.pbio.3002756. PubMed PMID: 39178182; PMCID: PMC11343374.
Graham JH, Schlachetzki JCM, Yang X, Breuss MW. Genomic Mosaicism of the Brain: Origin, Impact, and Utility. Neurosci Bull. 2023. Epub 20231029. doi: 10.1007/s12264-023-01124-8. PubMed PMID: 37898991.
Breuss MW*, Yang X*, Schlachetzki JCM*, Antaki D*, Lana AJ, Xu X, Chung C, Chai G, Stanley V, Song Q, Newmeyer TF, Nguyen A, O'Brien S, Hoeksema MA, Cao B, Nott A, McEvoy-Venneri J, Pasillas MP, Barton ST, Copeland BR, Nahas S, Van Der Kraan L, Ding Y, Network NBSM, Glass CK, Gleeson JG. Somatic mosaicism reveals clonal distributions of neocortical development. Nature. 2022;604(7907):689-96. Epub 2022/04/22. doi: 10.1038/s41586-022-04602-7. PubMed PMID: 35444276; PMCID: PMC9436791.
Breuss MW*$, Yang X*, Stanley V, McEvoy-Venneri J, Xu X, Morales AJ, Gleeson JG$. Unbiased mosaic variant assessment in sperm: a cohort study to test predictability of transmission. Elife. 2022;11. Epub 2022/07/06. doi: 10.7554/eLife.78459. PubMed PMID: 35787314; PMCID: PMC9255958.
Others (since 2021)
Yang X*, Xu X*, Breuss MW, Antaki D, Ball LL, Chung C, Shen J, Li C, George RD, Wang Y, Bae T, Cheng Y, Abyzov A, Wei L, Alexandrov LB, Sebat JL, Network NBSM, Gleeson JG. Control-independent mosaic single nucleotide variant detection with DeepMosaic. Nat Biotechnol. 2023;41(6):870-7. Epub 20230102. doi: 10.1038/s41587-022-01559-w. PubMed PMID: 36593400; PMCID: PMC10314968.
Chung C*, Yang X*, Bae T, Vong KI, Mittal S, Donkels C, Westley Phillips H, Li Z, Marsh APL, Breuss MW, Ball LL, Garcia CAB, George RD, Gu J, Xu M, Barrows C, James KN, Stanley V, Nidhiry AS, Khoury S, Howe G, Riley E, Xu X, Copeland B, Wang Y, Kim SH, Kang HC, Schulze-Bonhage A, Haas CA, Urbach H, Prinz M, Limbrick DD, Jr., Gurnett CA, Smyth MD, Sattar S, Nespeca M, Gonda DD, Imai K, Takahashi Y, Chen HH, Tsai JW, Conti V, Guerrini R, Devinsky O, Silva WA, Jr., Machado HR, Mathern GW, Abyzov A, Baldassari S, Baulac S, Focal Cortical Dysplasia Neurogenetics C, Brain Somatic Mosaicism N, Gleeson JG. Comprehensive multi-omic profiling of somatic mutations in malformations of cortical development. Nat Genet. 2023;55(2):209-20. Epub 2023/01/13. doi: 10.1038/s41588-022-01276-9. PubMed PMID: 36635388; PMCID: PMC9961399.
Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021;109(2):241-56 e9. Epub 2020/11/22. doi: 10.1016/j.neuron.2020.10.035. PubMed PMID: 33220177; PMCID: PMC8800389.
Ghosh SG, Scala M, Beetz C, Helman G, Stanley V, Yang X, Breuss MW, Mazaheri N, Selim L, Hadipour F, Pais L, Stutterd CA, Karageorgou V, Begtrup A, Crunk A, Juusola J, Willaert R, Flore LA, Kennelly K, Spencer C, Brown M, Trapane P, Hurst ACE, Lane Rutledge S, Goodloe DH, McDonald MT, Shashi V, Schoch K, Undiagnosed Diseases N, Tomoum H, Zaitoun R, Hadipour Z, Galehdari H, Pagnamenta AT, Mojarrad M, Sedaghat A, Dias P, Quintas S, Eslahi A, Shariati G, Bauer P, Simons C, Houlden H, Issa MY, Zaki MS, Maroofian R, Gleeson JG. A relatively common homozygous TRAPPC4 splicing variant is associated with an early-infantile neurodegenerative syndrome. Eur J Hum Genet. 2021;29(2):271-9. Epub 2020/09/10. doi: 10.1038/s41431-020-00717-5. PubMed PMID: 32901138; PMCID: PMC7868361 declare no conflict of interest.
Ghosh SG*, Breuss MW*$, Schlachetzki Z, Chai G, Ross D, Stanley V, Sonmez FM, Topaloglu H, Zaki MS, Hosny H, Gad S, Gleeson JG$. Biallelic hypomorphic mutations in HEATR5B, encoding HEAT repeat-containing protein 5B, in a neurological syndrome with pontocerebellar hypoplasia. Eur J Hum Genet. 2021;29(6):957-64. Epub 2021/04/08. doi: 10.1038/s41431-021-00832-x. PubMed PMID: 33824466; PMCID: PMC8187379.
Breuss MW*, Yang X*, Gleeson JG. Sperm mosaicism: implications for genomic diversity and disease. Trends Genet. 2021;37(10):890-902. Epub 2021/06/24. doi: 10.1016/j.tig.2021.05.007. PubMed PMID: 34158173; PMCID: PMC9484299.
Yang X*, Breuss MW*, Xu X, Antaki D, James KN, Stanley V, Ball LL, George RD, Wirth SA, Cao B, Nguyen A, McEvoy-Venneri J, Chai G, Nahas S, Van Der Kraan L, Ding Y, Sebat J, Gleeson JG. Developmental and temporal characteristics of clonal sperm mosaicism. Cell. 2021;184(18):4772-83 e15. Epub 2021/08/14. doi: 10.1016/j.cell.2021.07.024. PubMed PMID: 34388390; PMCID: PMC8496133.
For an up-to-date list and additional publications for Martin before 2021, please see the links to Google Scholar or PubMed.